Functional Longevity
Astaxanthin Benefits: The King of Carotenoids & Mitochondrial Shield
💡 What You Need to Know Right Away
- Powerful antioxidant: Astaxanthin has an oxygen radical absorbance capacity (ORAC) 100-500 times higher than α-tocopherol (vitamin E), making it one of nature's most potent free radical scavengers.[Evidence: D][7]
- Skin protection: Multiple clinical trials show astaxanthin significantly restores skin moisture content and improves elasticity compared to placebo.[Evidence: A][2]
- Anti-inflammatory effects: Meta-analysis of 12 RCTs demonstrates significant reduction in blood malondialdehyde (oxidative damage marker) and interleukin-6 in diabetic patients.[Evidence: A][3]
- Heart health support: At 12mg daily, HDL-C improved from 55±8 to 63±8 mg/dL, with triglycerides reduced from 151±26 to 112±40 mg/dL at 18mg daily doses.[Evidence: A][1]
If you have been researching natural antioxidants for skin health, brain function, or overall longevity, you have likely encountered astaxanthin. This red-pigmented carotenoid from marine algae has generated significant scientific interest, with 17 clinical studies now supporting its health applications.
What makes astaxanthin unique? Unlike most antioxidants, it can cross the blood-brain barrier and integrate directly into cell membranes, providing protection where other compounds cannot reach.[Evidence: D][7] This comprehensive guide examines the evidence-based benefits, proper dosage protocols, safety considerations, and practical recommendations to help you make informed decisions about this promising supplement.
❓ Quick Answers
What is astaxanthin?
Astaxanthin is a red-pigmented carotenoid antioxidant primarily derived from Haematococcus pluvialis microalgae. It belongs to the xanthophyll class and is responsible for the pink color in salmon, shrimp, and flamingos. Natural astaxanthin exists predominantly as the 3S,3'S stereoisomer in esterified form, which research suggests has superior bioavailability compared to synthetic versions.[Evidence: D][8]
How does astaxanthin work?
Astaxanthin works by spanning cell membranes with its polar end groups positioned on both sides, allowing it to neutralize free radicals throughout the membrane structure. It enhances fat oxidation during aerobic exercise and modulates multiple signaling pathways including Nrf2 and NF-κB.[Evidence: A][4] This unique positioning provides broad antioxidant protection.
What are the benefits of astaxanthin?
Clinical research supports benefits for skin health (improved moisture and elasticity), eye health (reduced digital eye strain by 20-27%), joint comfort (reduced RA symptoms), and cardiovascular markers (improved HDL-C and reduced triglycerides).[Evidence: A][2][6] Effects on cognitive function show marginally significant improvements in accuracy.[Evidence: A][4]
What foods contain astaxanthin?
Natural food sources include wild-caught sockeye salmon (highest at approximately 4.5mg per 4oz serving), rainbow trout, Arctic shrimp, krill, red crab, and lobster. However, achieving therapeutic dosages of 4-12mg daily through diet alone is challenging, which is why supplementation from Haematococcus pluvialis algae is commonly recommended.[Evidence: D][10]
How much astaxanthin should I take?
Clinical studies have used dosages ranging from 3-20mg daily depending on the health goal. For general antioxidant support and skin health, 3-6mg daily is commonly recommended. For joint inflammation or cardiovascular benefits, studies have used 12-20mg daily for 8-24 weeks.[Evidence: A][10][5]
Is astaxanthin safe to take every day?
A comprehensive safety review of 87 human clinical trials found no safety concerns with daily astaxanthin use. Thirty-five of these trials used doses at or above 12mg/day without safety issues. Natural astaxanthin has GRAS (Generally Recognized As Safe) status.[Evidence: D][8] The most common benign effect is red or pink stool coloration.
How long does it take for astaxanthin to work?
Timeline varies by benefit area. Peak blood concentration occurs 8-10 hours after ingestion. Skin improvements (moisture, elasticity) typically appear within 8-12 weeks. Eye health benefits were observed after 84 days in clinical trials. Joint pain reduction in rheumatoid arthritis patients showed significant effects at 8 weeks.[Evidence: B][6][5]
Astaxanthin
Benefits
Derived primarily from microalgae, Astaxanthin is the most powerful antioxidant found in nature. Explore how this "King of Carotenoids" transforms human health from the inside out.
🔬 How Does Astaxanthin Work?
Think of astaxanthin as a security guard that can patrol both inside and outside your cells simultaneously. Most antioxidants can only work on one side of a cell membrane, but astaxanthin's unique molecular structure allows it to span the entire membrane, positioning its polar end groups on both the inner and outer surfaces. This gives it exceptional ability to neutralize harmful free radicals wherever they occur.
At the molecular level, astaxanthin demonstrates an oxygen radical absorbance capacity (ORAC) that is 100-500 times higher than α-tocopherol (vitamin E).[Evidence: D][7] This remarkable potency comes from its extended conjugated double bond system, which can quench singlet oxygen and neutralize reactive oxygen species with exceptional efficiency.
The compound exerts its effects through multiple biochemical pathways. Research shows astaxanthin modulates the PI3K/AKT, Nrf2, NF-κB, ERK1/2, JNK, p38 MAPK, and JAK-2/STAT-3 signaling pathways.[Evidence: D][12] By activating Nrf2, astaxanthin upregulates the body's own antioxidant defense systems. By inhibiting NF-κB, it reduces inflammatory signaling.
Imagine your mitochondria as power plants that generate energy but also produce pollution (free radicals). Astaxanthin integrates directly into mitochondrial membranes, protecting these cellular powerhouses from oxidative damage and preserving their ATP production capacity.[Evidence: D][11]
In clinical studies, these mechanisms translate to measurable outcomes. A meta-analysis of 12 RCTs (380 participants) demonstrated that astaxanthin supplementation significantly reduced blood malondialdehyde (a marker of oxidative damage), improved superoxide dismutase activity in overweight subjects, and significantly lowered interleukin-6 levels in diabetic patients.[Evidence: A][3] Another meta-analysis found significantly improved total antioxidant capacity in follicular fluid of women with PCOS.[Evidence: A][9]
📊 Dosage and How to Use
Clinical research provides clear dosage guidelines based on specific health goals. The following table summarizes evidence-based dosing protocols from validated clinical trials.
| Purpose/Condition | Dosage | Duration | Evidence |
|---|---|---|---|
| Skin health/photoaging | 3-6 mg/day | 8-12 weeks | [A][10] |
| Digital eye strain (children) | 6 mg/day | 84 days | [B][6] |
| Rheumatoid arthritis | 20 mg/day | 8 weeks | [B][5] |
| PCOS (reproductive outcomes) | 6 mg/day | 8 weeks | [B][14] |
| HDL-C improvement | 12 mg/day | 12 weeks | [A][1] |
| LDL/cholesterol reduction (prediabetes) | 12 mg/day | 24 weeks | [B][16] |
| Triglyceride reduction | 18 mg/day | Variable | [A][1] |
Absorption and Timing
Astaxanthin is fat-soluble, meaning it requires dietary fat for optimal absorption. Take your supplement with a meal containing healthy fats such as olive oil, avocado, nuts, or fatty fish. Peak blood concentration occurs approximately 8-10 hours after ingestion. Timing (morning vs. evening) appears flexible based on current evidence, though taking it with your largest meal may optimize absorption.
Important: Consult your healthcare provider before starting astaxanthin supplementation, particularly if you have underlying health conditions or take medications. These dosages are derived from clinical research and may not be appropriate for everyone.
⚠️ Risks, Side Effects, and Warnings
⚠️ Important Safety Information
- Warfarin interaction documented: A case report describes a 69-year-old woman whose INR spiked from 1.4 to 10.38 within 1 day of starting astaxanthin while taking warfarin, resulting in ecchymosis on groin and thigh.[13]
- Blood thinners: Do not take astaxanthin with warfarin, aspirin, or other anticoagulants without physician approval due to potential bleeding risk.
- Pregnancy/breastfeeding: Insufficient safety data exists. Avoid use unless clinically indicated and approved by your doctor.
- Surgery: Discontinue at least 2 weeks before scheduled surgery due to potential bleeding effects.
Side Effects by Frequency
A comprehensive safety review of 87 human clinical trials found no serious safety concerns with astaxanthin supplementation.[Evidence: D][8] Thirty-five trials used doses at or above 12mg/day without documenting safety issues. Common benign effects include:
- Red or pink stool color - This is harmless and results from the pigment being excreted
- Mild stomach upset - Usually occurs when taken without food
- Increased bowel movements - Reported occasionally
A subchronic toxicity study in rats showed no effects on survival, clinical examinations, sperm parameters, or estrous cycle at very high doses (up to 700-920 mg/kg bw/day), with the only observable change being GI content discoloration.[Evidence: C][17]
Drug Interactions
In vitro research found that astaxanthin showed no apparent inhibition of human UDP-glucuronosyl-transferase (UGT) enzymes, suggesting it is unlikely to cause supplement-drug interactions via hepatic UGT inhibition.[Evidence: B][15] However, the documented warfarin interaction indicates that clinically significant interactions can occur with blood thinners through other mechanisms. Inform your healthcare provider of all medications before starting astaxanthin.
Who Should NOT Take Astaxanthin
- Individuals taking warfarin or other blood thinners without physician supervision
- Pregnant or breastfeeding women (insufficient safety data)
- People with known allergies to algae, seafood, or carotenoids
- Anyone scheduled for surgery within 2 weeks
🥗 Practical Ways to Use Astaxanthin
How to Use This in Your Daily Life
Scenario 1: Skin Health and Photoprotection
- Dose: 3-6mg daily[10]
- Duration: 8-12 weeks for visible results[2]
- Population: Adults seeking improved skin hydration and elasticity
- Timing: With breakfast or lunch containing healthy fats
- What to track: Skin moisture, elasticity, wrinkle appearance
- Expected results: Significantly restored skin moisture content and improved elasticity compared to placebo[2]
Note: Astaxanthin is NOT a replacement for sunscreen. Use alongside topical SPF protection for UV defense.
Scenario 2: Joint Health (Rheumatoid Arthritis)
- Dose: 20mg daily[5]
- Duration: 8 weeks
- Population: Adults with rheumatoid arthritis (as complement to medical treatment)
- What to track: DAS-28 score, pain levels, ESR, CRP if tested
- Expected results: Significant reductions in DAS-28, HAQ, ESR, and CRP levels[5]
Scenario 3: Cardiovascular Support
- Dose: 12mg daily[16]
- Duration: 12-24 weeks
- Population: Adults with dyslipidemia or prediabetes
- What to track: Lipid panel (HDL-C, LDL, triglycerides, total cholesterol)
- Expected results: HDL-C improvement, LDL reduced by -0.33 ± 0.11 mM, total cholesterol reduced by -0.30 ± 0.14 mM[16]
Practical Integration
Take your astaxanthin supplement with a meal containing fat for optimal absorption. Pair with foods like salmon (which naturally contains astaxanthin), eggs cooked in olive oil, or avocado toast. Store in a cool, dry place away from direct sunlight to preserve potency.
Common Mistakes to Avoid
- Taking on an empty stomach: Fat-soluble supplements absorb poorly without dietary fat. Always take with meals.
- Inconsistent dosing: Studies used daily dosing protocols[5][16]. Sporadic use may not achieve the benefits observed in clinical trials.
- Expecting immediate results: Clinical benefits typically require 8-12 weeks of consistent use.
- Choosing synthetic over natural: Natural astaxanthin from H. pluvialis chemically differs from synthetic versions, and the safety review recommends separate guidelines for each.[8]
⚖️ Astaxanthin vs. Other Antioxidants
How does astaxanthin compare to other popular antioxidants? The following table provides a balanced comparison based on available research.
| Feature | Astaxanthin | Vitamin E (α-tocopherol) | CoQ10 |
|---|---|---|---|
| Relative ORAC potency | 100-500x higher than vitamin E[7] | Baseline | Lower than astaxanthin |
| Crosses blood-brain barrier | Yes | Limited | Yes |
| Membrane positioning | Spans entire membrane[11] | One side only | Within membrane |
| Primary source | Haematococcus pluvialis algae | Vegetable oils, nuts | Organ meats, fish |
| Fat-soluble | Yes | Yes | Yes |
| Cardiovascular evidence | HDL-C and triglyceride improvement[1] | Mixed results | Heart failure support |
| Skin benefits | Strong evidence[2] | Moderate evidence | Limited evidence |
Astaxanthin's unique molecular structure provides advantages in membrane protection that other antioxidants cannot match. Its strong antioxidant capability stems from both its molecular composition and its ability to position itself across cell membranes.[Evidence: D][11] However, this does not mean astaxanthin replaces other antioxidants. Each serves different functions in the body's antioxidant network.
For cardiovascular benefits specifically, a 24-week RCT in 34 adults with prediabetes showed astaxanthin (12mg daily) reduced LDL by -0.33 ± 0.11 mM and total cholesterol by -0.30 ± 0.14 mM, while also decreasing fibrinogen, L-selectin, and fetuin-A.[Evidence: B][16]
What The Evidence Shows (And Doesn't Show)
What Research Suggests
- Skin health: Strong evidence from meta-analysis of 9 RCTs shows significantly restored skin moisture content and improved elasticity compared to placebo at 3-6mg daily for 8-12 weeks.[Evidence: A][2]
- Cardiovascular markers: Meta-analysis of 8 RCTs demonstrates HDL-C improved from 55±8 to 63±8 mg/dL at 12mg daily; triglycerides reduced from 151±26 to 112±40 mg/dL at 18mg daily. No significant impact on LDL or total cholesterol in the meta-analysis.[Evidence: A][1]
- Anti-inflammatory effects: Meta-analysis of 12 RCTs (380 participants) shows significant reduction in blood malondialdehyde and IL-6, particularly strong in type 2 diabetes patients.[Evidence: A][3]
- Joint health: Single RCT (n=60) found 20mg daily for 8 weeks significantly reduced DAS-28, HAQ, ESR, and CRP in rheumatoid arthritis patients.[Evidence: B][5]
- Eye health: Single RCT (n=64) found 6mg daily for 84 days improved digital eye strain scores by 20-27% in children.[Evidence: B][6]
What's NOT Yet Proven
- Wrinkle reduction: Meta-analysis found astaxanthin did not substantially decrease wrinkle depth despite improving moisture and elasticity.[2]
- Cognitive enhancement: Only marginally significant improvements in cognitive accuracy observed; no meaningful change in reaction time.[4]
- Long-term safety: Most clinical trials lasted 8-12 weeks. Long-term safety data beyond 24 weeks remains limited.
- Pregnancy/lactation safety: No clinical trials have evaluated safety in pregnant or breastfeeding women.
- Fertility improvement: While oocyte quality improved, pregnancy rates were not significantly different from placebo.[9]
- Optimal dosage: Studies used 3-20mg daily with varying results; the therapeutic threshold for each benefit has not been definitively established.
Where Caution Is Needed
- Warfarin interaction: Documented case report of INR spiking from 1.4 to 10.38 within 1 day, causing bleeding complications.[Evidence: C][13]
- Natural vs. synthetic: Safety data applies to natural astaxanthin from H. pluvialis. Synthetic forms require separate evaluation.[8]
- Cardiovascular findings: Meta-analysis found no significant impact on LDL cholesterol or total cholesterol, though one individual RCT showed reductions.[1][16]
- RA study limitations: Joint health findings come from a single 8-week RCT. Pain reduction was only marginally significant after baseline adjustment.[5]
Should YOU Try This?
Best suited for: Adults seeking antioxidant support for skin health, individuals with dyslipidemia interested in HDL-C improvement, people experiencing digital eye strain, and those with rheumatoid arthritis looking for complementary support alongside medical treatment.
Not recommended for: Individuals taking warfarin or other blood thinners without physician supervision, pregnant or breastfeeding women, people with algae or seafood allergies, and anyone scheduled for surgery within 2 weeks.
Realistic timeline: Skin improvements typically appear in 8-12 weeks. Eye health benefits observed at 84 days. Cardiovascular marker changes demonstrated at 12-24 weeks. Joint health improvements at 8 weeks.
When to consult a professional: Before starting astaxanthin if you take any medications (especially blood thinners or blood pressure medications), have underlying health conditions, or are pregnant, breastfeeding, or planning surgery.
Frequently Asked Questions
Can I take astaxanthin with other supplements?
In vitro research suggests astaxanthin is unlikely to cause supplement-drug interactions via hepatic UGT enzyme inhibition. Astaxanthin is commonly combined with omega-3 fatty acids (which may enhance absorption), vitamin E, and CoQ10 without documented adverse interactions. However, caution is warranted when combining with blood-thinning supplements like fish oil, ginkgo biloba, or vitamin E in high doses, as these may compound potential bleeding effects. A documented case showed dangerous interaction with warfarin. Always inform your healthcare provider about all supplements you take.
Is natural astaxanthin better than synthetic?
The comprehensive safety review notes that natural astaxanthin chemically differs from synthetic forms and recommends separate safety guidelines for each. Natural astaxanthin from Haematococcus pluvialis exists predominantly as the 3S,3'S stereoisomer in esterified form, while synthetic versions contain a mixture of stereoisomers. The 87 human clinical trials reviewed used natural astaxanthin, so the established safety profile specifically applies to the natural form. Synthetic astaxanthin is approved for aquaculture but not well-studied for human consumption.
Does astaxanthin cross the blood-brain barrier?
Yes, astaxanthin is one of the few antioxidants that can cross the blood-brain barrier. This property, combined with its ability to integrate into cell membranes, allows it to provide neuroprotective effects directly within brain tissue. The compound modulates signaling pathways including PI3K/AKT and Nrf2 that are relevant to neurological protection. A meta-analysis found marginally significant improvements in cognitive accuracy with supplementation, though effects on reaction time were not meaningful. Stronger benefits were observed at doses ≥20mg and duration >12 weeks.
Can astaxanthin improve athletic performance?
Evidence for athletic performance is mixed. A meta-analysis of 11 RCTs (346 healthy participants) found astaxanthin enhanced fat oxidation during aerobic exercise but showed no meaningful change in reaction time. The meta-analysis noted stronger benefits at doses ≥20mg and duration >12 weeks. These findings suggest astaxanthin may support metabolic efficiency during exercise, but should not be expected to dramatically improve performance. Individual response varies based on training status, baseline fitness, and study protocols. Athletes interested in astaxanthin should view it as a supportive supplement rather than a performance enhancer.
Can astaxanthin help with skin aging?
Multiple clinical trials support astaxanthin for skin health. A systematic review of 11 clinical studies (including 6 RCTs) found improved skin texture, appearance (wrinkles), and moisture content, along with protection against UV damage at 3-6mg daily. A separate meta-analysis confirmed that oral astaxanthin significantly restored skin moisture content and improved elasticity compared to placebo, though it did not substantially decrease wrinkle depth. Effects typically require 8-12 weeks of consistent supplementation to become apparent.
Is astaxanthin good for eye health?
Yes, clinical research supports eye health benefits. A randomized double-blind placebo-controlled trial in 64 children (ages 10-14) over 84 days found astaxanthin significantly improved CVS-Q scores (digital eye strain) with a 20% between-group difference. Visual fatigue scores decreased 27% more in the treatment group, with additional improvements in stereopsis, pupillary light reflex, and increased tear production. The comprehensive review also notes benefits for ocular health among astaxanthin's therapeutic applications.
Is astaxanthin safe during pregnancy?
Insufficient safety data exists for astaxanthin use during pregnancy and breastfeeding. No clinical trials have specifically evaluated safety in pregnant or lactating women. While the safety review of 87 human trials found no concerns in the general population, this does not extend to pregnant women. The precautionary principle applies: avoid astaxanthin during pregnancy and breastfeeding unless clinically indicated and specifically approved by your healthcare provider. If you become pregnant while taking astaxanthin, discontinue use and consult your doctor.
Can astaxanthin help with PCOS or fertility?
Two studies have examined astaxanthin in women with PCOS. An RCT of 44 women undergoing assisted reproductive technology found 6mg daily for 8 weeks significantly decreased IL-6 and IL-1β concentrations in serum and resulted in higher numbers of retrieved eggs, mature oocytes, and frozen embryos, though pregnancy rates were not meaningfully different. A meta-analysis found significantly improved total antioxidant capacity in follicular fluid and moderate improvements in oocyte quality and embryo development, but effects on fertilization and pregnancy rates were not significant.
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At Biochron, we take health information seriously. Every claim in this article is supported by peer-reviewed scientific evidence from reputable sources published in 2015 or later. We use a rigorous evidence-grading system to help you understand the strength of research behind each statement:
- [Evidence: A] = Systematic review or meta-analysis (strongest evidence)
- [Evidence: B] = Randomized controlled trial (RCT)
- [Evidence: C] = Cohort or case-control study
- [Evidence: D] = Expert opinion or clinical guideline
Our editorial team follows strict guidelines: we never exaggerate health claims, we clearly distinguish between correlation and causation, we update content regularly as new research emerges, and we transparently note when evidence is limited or conflicting. For our complete editorial standards, visit our Editorial Principles page.
This article is for informational purposes only and does not constitute medical advice. Always consult qualified healthcare professionals before making changes to your health regimen, especially if you have medical conditions or take medications.
References
- 1 . Assessing the Effects of Moderate to High Dosage of Astaxanthin Supplementation on Lipid Profile Parameters-A Systematic Review and Meta-Analysis of Randomized Controlled Studies, Fornari Laurindo L et al., Pharmaceuticals (Basel, Switzerland), 2025, Vol. 18(8), PubMed, DOI [Evidence: A]
- 2 . Systematic Review and Meta-Analysis on the Effects of Astaxanthin on Human Skin Ageing, Zhou X et al., Nutrients, 2021, Vol. 13(9), PubMed, DOI [Evidence: A]
- 3 . Astaxanthin supplementation mildly reduced oxidative stress and inflammation biomarkers: a systematic review and meta-analysis of randomized controlled trials, Ma B et al., Nutrition research, 2022, Vol. 99, pp. 40-50, PubMed, DOI [Evidence: A]
- 4 . Effects of Astaxanthin Supplementation on Fatigue, Motor Function and Cognition: A Meta-Analysis of Randomized Controlled Trials, Liu C et al., Biological research for nursing, 2024, Vol. 26(3), pp. 469-480, PubMed, DOI [Evidence: A]
- 5 . Astaxanthin supplement improves clinical outcomes, quality of life, and inflammatory factors in patients with rheumatoid arthritis: a randomized clinical trial, Grigorian A et al., Food & function, 2025, Vol. 16(14), pp. 5850-5858, PubMed, DOI [Evidence: B]
- 6 . Astaxanthin (AstaReal®) Improved Acute and Chronic Digital Eye Strain in Children: A Randomized Double-Blind Placebo-Controlled Trial, Hecht KA et al., Advances in therapy, 2025, Vol. 42(4), pp. 1811-1833, PubMed, DOI [Evidence: B]
- 7 . Therapeutic uses of natural astaxanthin: An evidence-based review focused on human clinical trials, Donoso A et al., Pharmacological research, 2021, Vol. 166, p. 105479, PubMed, DOI [Evidence: D]
- 8 . Astaxanthin: How much is too much? A safety review, Brendler T & Williamson EM, Phytotherapy research, 2019, Vol. 33(12), pp. 3090-3111, PubMed, DOI [Evidence: D]
- 9 . Exploring the benefits of astaxanthin as a functional food ingredient: Its effects on oxidative stress and reproductive outcomes in women with PCOS, Rodrigues VD et al., Naunyn-Schmiedeberg's archives of pharmacology, 2025, Vol. 398(2), pp. 1155-1169, PubMed, DOI [Evidence: A]
- 10 . Effects of Astaxanthin Supplementation on Skin Health: A Systematic Review of Clinical Studies, Ng QX et al., Journal of dietary supplements, 2021, Vol. 18(2), pp. 169-182, PubMed, DOI [Evidence: A]
- 11 . Antioxidant and anti-inflammatory mechanisms of action of astaxanthin in cardiovascular diseases (Review), Pereira CPM et al., International journal of molecular medicine, 2021, Vol. 47(1), pp. 37-48, PubMed, DOI [Evidence: D]
- 12 . Anti-inflammatory action of astaxanthin and its use in the treatment of various diseases, Kohandel Z et al., Biomedicine & pharmacotherapy, 2022, Vol. 145, p. 112179, PubMed, DOI [Evidence: D]
- 13 . Interaction between warfarin and astaxanthin: A case report, Santiyanon N & Yeephu S, Journal of cardiology cases, 2019, Vol. 19(5), pp. 173-175, PubMed, DOI [Evidence: C]
- 14 . Astaxanthin treatment decreases pro-inflammatory cytokines and improves reproductive outcomes in patients with polycystic ovary syndrome undergoing assisted reproductive technology, Fereidouni F et al., Inflammopharmacology, 2024, Vol. 32(4), pp. 2337-2347, PubMed, DOI [Evidence: B]
- 15 . In Vitro Inhibition of Human UDP-Glucuronosyl-Transferase (UGT) Isoforms by Astaxanthin, β-Cryptoxanthin, Canthaxanthin, Lutein, and Zeaxanthin, Zheng YF et al., Molecules, 2016, Vol. 21(8), PubMed, DOI [Evidence: B]
- 16 . Astaxanthin, a natural antioxidant, lowers cholesterol and markers of cardiovascular risk in individuals with prediabetes and dyslipidaemia, Ciaraldi TP et al., Diabetes, obesity & metabolism, 2023, Vol. 25(7), pp. 1985-1994, PubMed, DOI [Evidence: B]
- 17 . Safety assessment of [3S, 3'S]-astaxanthin--Subchronic toxicity study in rats, Buesen R et al., Food and chemical toxicology, 2015, Vol. 81, pp. 129-136, PubMed, DOI [Evidence: C]
Medical Disclaimer
This content is for informational and educational purposes only. It is not intended to provide medical advice or to take the place of such advice or treatment from a personal physician. All readers are advised to consult their doctors or qualified health professionals regarding specific health questions and before making any changes to their health routine, including starting new supplements.
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